Some chemical reactions, like those used to produce the active ingredients for the popular statin drugs, must occur at low temperatures of approximately 100C (148F). 202 0 obj <> endobj Store all containers with cryogens, pressurized or non-pressurized, in well ventilated areas. Seek medical attention. This is no accident. University of Texas at Austin students, faculty, staff, and affiliate researchers who work in labs containing cryogen materials must complete OH 241 Cryogen Safety training. Do not permit liquid oxygen or oxygen rich atmosphere to come into contact with organic materials or flammable substances of any kind. Generally,chemical-splash gogglesandface shieldsshould always be worn during the transfer and handling process of cryogenic liquids to guard against splashes and spills. These liquids have boiling points below 238 F (150 C) and are gases at normal room temperatures and pressures. Which of the following "fundamentals" of biological safety are true? People with frostbitten feet should not walk on them. According to United States Department of Transportation (DOT) and Occupational Safety and Health Administration (OSHA) regulations, the labeling must list contents, concentrations, hazard classifications, safety precautions and the manufacturer or supplier. Remove or loosen clothing that may restrict blood flow to the frozen area. If cryogenic liquids have to be used or stored in a poorly ventilated area, or if large amounts could potentially be released and cause oxygen deficiency, an oxygen monitor should be installed. - begins with a review of scientific literature. 521525. This condition can result in an explosion caused by the build up of trapped vapor in the container. Our two departments provide fundamental and applied studies of an outstanding caliber. of the 26th Intersociety Energy Conversion Engineering Conference, Vol. Allow excess cryogens to evaporate naturally in a well-ventilated place. Februar 2022; Beitrags-Kategorie: minnesota wild covid rules minnesota wild covid rules Most of them have no color as a liquid although liquid oxygen is light blue. W3J/ox/_J||\ ?Q:A(>3m [zW|B,)>azq!eMS,3fJ'i^ Prevent infection--use a mild soap to clean the affected area. If working in an area where an oxygen-deficient atmosphere could be produced due to the off-gassing of cryogenic liquids or dry ice, an air-supplying respirator must be used, such as anairline respiratorwith an egress bottle or a self-contained breathing apparatus (SCBA). Researchers should wash their hands and arms with soap and water, rinsing and drying thoroughly prior to handling the liquid. Classification Emergency Procedures Room Signage Labeling Cylinder status tags Gas delivery systems Regulators Procurement Other applications include fast freezing of some foods and the preservation of some biological materials. The concentration of oxygen can reach as high as 80% and amplify flammability and explosion hazards. Any exposed glass areas of dewars should be taped to prevent the generation of broken glass projectiles in the event the container implodes. The central mission of the College of Chemistry is to advance society through education and research, and we have made it our responsibility to fulfill this mission, year in and year out, for more than 140 years. Another use of cryogenics is cryogenic fuels for rockets with liquid hydrogen as the most widely used example. Even non-metallic materials are dangerous to touch at low temperatures. This document describes the principal hazards and appropriate safety procedures associated with three cryogenic liquids that are commonly used in the College: liquid N2, He and O2. They should also be loose fitting for cryogenic liquids, so they can be easily removed if a cryogenic liquid spill should go inside the glove. Do not transport cryogenic liquids in open dewars. These liquids have boiling points below -238F (-150C) and are gases at normal temperatures and pressures. What are 'Dark Factories,' and Do They Really Exist? When you contribute to the exceptional scholarship of our students and faculty, you help to improve the lives of people all over the world. cold temperatures associated with the use of cryogens The class of gases that are termed compressed gases are non-liquefied gases. The best control measure is to minimize the accumulation of oxygen coming into contact with the cryogenand to keep containers free of hydrocarbon contamination. However, where cryogenic liquids and dry ice are involved, metallic materials are not the only ones that cause this risk. cold temperatures associated with the use of cryogens. Cryogens are liquefied gases that are stored and dispensed at extremely low temperatures. Substances that burn in air will burn more vigorously in oxygen. 1994-2020, W.W. Grainger, Inc. All Rights Reserved. Keep all sources of ignition away from cryogenic liquids. The gloves must be loose so they can be thrown off quickly if cryogenic liquid spills into them. Springer Science+Business Media LLC (2007). Does Cold Weather Cause Colds? | Live Science which statements apply to physical hazards in the laboratory? Stanford University: SLAC Environment, Safety, and Health Manual, Chapter 36: Cryogenic and Oxygen Deficiency Hazard Safety http://www-group.slac.stanford.edu/esh/eshmanual/pdfs/ESHch36.pdf (accessed Dec 2013). Because of their large liquid to gas expansion ratios, even small quantities of liquefied gas can expand to displace large amounts of oxygen, thereby rendering the atmosphere in a confined area lethal. The basic model used in assessing the toxicity of a chemical includes its route(s) of entry into the body and, emergency response experts recommend that you should be prepared to take of yourself (and those that depend on you) in you home for approximately ____ hours after a major disaster, Assignment 11 - Eyes & Face Safety and Protec, Nutr 304 childhood pt 4 - middle childhood an, Patho Chapter 26 Stress and Associated Proble. Pants without cuffs that can trap liquid next to your body. endstream endobj startxref Do not use Teflon tape, putty or other such materials on the threads unless specifically required (or applied) by the manufacturer or vendor. Cryogens, such as liquid nitrogen and helium, are liquefied gases that are kept in their liquid state at very low temperatures. The touching of uninsulated containers or other materials that have been cooled by cryogenic liquids can cause serious skin injuries. Bulk storage and container transport of cryogenic gases is in liquid, double-walled, vacuum-sealed containers that can be eitherpressurizedornon-pressurized. yazan kategorisi how to look up beckett graded cards ak Yaymlanma tarihi 9 Haziran 2022 kategorisi how to look up beckett graded cards ak Yaymlanma tarihi 9 Haziran 2022 Liquid nitrogen is the most frequently used cryogen on campus. A: Nitrogen condenses to a liquid at 320F. Closed toed shoes are required when handling cryogenic liquids. `fub;TgdZ`8 Oxygen-enriched atmospheres may lead to violent reactions, such as rapid combustion or explosions, with incompatible materials. A good face shield should have adjustments to fit many head sizes and should provide good coverage of the entire front of the head, including around the sides. Make sure that ice buildup is not blocking the safety devices of the cylinder. HELP. Quick Tips #290.1. A liquid having a vapor pressure exceeding 40 psi at 100 F (38 C); as determined by ASTM D-323-72. ALL toxic and highly toxic gases are purchased through Praxair, unless unavailable. Liquid helium must be transferred through a vacuum-insulated tube because of its extremely low heat of vaporization. Have pot holders or appropriate gloves on hand. If skin or the eyes are exposed to cryogens or the cold vapor, use warm water (up to 108 F/42 C, NOT above 112 F/44 C) to restore normal body temperature. To dispose of your compressed gas cylinders, ask yourself these questions: For example, when you procure a gas cylinder from Praxair, you buy the gas but rent the cylinder (pay demurrage). cold temperatures associated with the use of cryogens ]mk/\O C ryogenics is a term normally associated with low temperatures. Contact with and destruction of living tissues. The basic PPE that should be worn 0;8?O90XXN | \O9-Pa|XdpAjAgf?pjEK=oI9Sa2+6G@\)91omcTCFl,"qn@f_9M4w]-{aPldVQ6Bm,[{}p2U- 7\%U(9qKAA5q. Also, when cryogenic liquids and dry ice form a gas, the gas is very cold and some are heavier than air. Hand protection is primarily required to guard against the hazard of touching cold surfaces. They are either: Examples include: helium, nitrogen, oxygen, and argon. Compressed Gas / Cryogenic Fluids | EHS Liquefied gases, such as liquid nitrogen and liquid helium, are used in many cryogenic applications. Non-pressurizedcontainers are typically open-topped vessels or Dewars with loose fitting covers to minimize evaporation or off gassing and range from one to 50 liters in size. The methods disclosed are suitable for removing the solvents with a broad range of volatility, having normal (STP) boiling points from 30 up to at least 202 C. (vapor pressures at least of 0.1 to 500 torr; higher boiling point . This definition includes liquid nitrogen (LN2), liquid argon (LAr), liquid helium (LHe), liquid hydrogen (LH2), and liquid oxygen (LO2), among others. By international agreement, a commercially purchased lab chemical today must include: for agents capable of causing a treatable or preventable disease in humans, for agents causing serious human or potentially lethal human disease, for which some treatment exists, specially designed for highly contagious agents for which no treatment or vaccination exists, and require extensive training. They have a loose-fitting cap or plug that prevents air and moisture from entering yet allows excess pressure to vent. hXYOI+3}H1XZ(&h}hU{Rve}UWW a%2^AtTK,wZL[KV1[fyQs:*6+d%`IxnpxZ r4]1znb5poesXbKZMU;x346G]wdq2+i`}^Mf,QbX/?4c*y~X3U/MIs.I--vy3#?N&.vvq:qjh)(g~06,]3Y]vUg.1hDNdbtvY/hYE{:"j%7\7''7!D?yC:+yL \IzD\n\w|~5H&sU;kcihvV||0_i|^=>Vd!*?8tk?Ih`PU0q;DkF%~lyAF$i!DimD:*G|*8Ozt_S^>ms{=:6!Be*>F>,!=~n=x>HP+q#MQ=eXW7)s These classifications are different and overlap in some ways. Cryogenic liquids flow very freely and can penetrate woven or other porous clothing. Oxygen deficiency might make the area unsafe to enter. Readers with specific questions should refer to the applicable standards or consult with an attorney. Methods of Solvent Removal at Ambient Temperatures - Cryovap Even well-ventilated lab spaces that have pits or other low-lying areas could have the oxygen displaced by this cold, dense gas. Cryogens UF | EHS - University of Florida OSHA: Compressed Gases, 20 UW Environmental Health & Safety Department | 201 Hall Health Center, Box 354400, Seattle, WA | Tel: 206.543.7262 | Fax: 206.543.3351 | ehsdept@uw.edu, Fume Hoods: Use, Inspection and Maintenance, Building Emergency Procedures and Resources, Fire Code Hazardous Materials (HazMat) Compliance, Radiation Detection Instrument Calibration, Use of Radiation in Human Subjects Research, UW Research & Training Building Remediation, Asbestos and Other Regulated Building Materials, Hazardous Energy Control - Lockout/Tagout, GHS-DOTClassification Comparisons Relevant to Compressed Gases, Transporting Compressed Gases and CryogensFocus Sheet, WAC: Permissible Exposure Limits for Airborne Contaminants, Transporting Compressed Gases and Cryogens, GHS DOT Classification Comparisons Relevant to Compressed Gases, A Guide to the Globally Harmonized System of Classification and Labeling of Chemicals (OSHA), List of Chemicals Immediately Dangerous to Life and Health (IDLH). 2 0 obj Small quantities of liquid nitrogen or liquid argon may be transported in and around buildings provided they are contained within an appropriate low pressure dewar (fitted with a lid) and carried by their handles. C2H5I(g)C2H4(g)+HI(g). 0 A: Gloves should be insulated and made to withstand the low temperatures of cryogenic liquids and dry ice. Cryogenic liquids are liquefied gases created by cooling a liquid to a low temperature under high pressure, which creates special health and safety hazards. The most likely cause of frostbite to the hands and body is by contact with cold metal surfaces. Maine - 41 degrees Fahrenheit. K,k=7.2104s1; at 720. All Rights Reserved. A cryogenic liquid is defined as a liquid with a normal boiling point below -240F (-150C, 123K). The freezing of portions of the body to destroy unwanted or malfunctioning tissue is known as cryosurgery. This page was last edited on 28 February 2023, at 03:09. cold temperatures associated with the use of cryogens To protect any exposed skin, long-sleeve shirts and trousers without cuffs are suggested. Rhinoviruses, which are the most common cause for colds, are better able to reproduce at temperatures just below the body's 98.6 degrees Fahrenheit. An occasional hissing sound from a cylinder indicates normal operation of the pressure relief valve as the liquid slowly evaporates. Cryogens have boiling points below -150C (- 238F), although carbon dioxide and nitrous oxide have slightly higher boiling points and are often included . Liquid hydrogen and liquid helium are both so cold that they can liquefy air on contact resulting in an oxygen-enriched atmosphere. Cryogens have boiling points below - 73 C (- 100 F) at 14.7 psia (an absolute pressure of 101kPa). Cylinders and Dewars are particularly vulnerable to damage during transport. cold temperatures associated with the use of cryogens The course covers the following topics: University of Florida Cryogens should never be brought onto a bus or shuttle. Store in a well ventilated area to prevent buildup of flammable gases or air displacement. Oxygen comprises about 21 percent of normal air. High pressure cylinders are equipped with a vent valve, liquid valve, gas valve, and pressure building valve. Leave the area immediately and get to a source of fresh air. GHS-Globally Harmonized System (HazCom) - Online, NFPA 55 - Compressed gas and Cryogenic Fluids Code, WAC: Permissible Exposure Limits for Airborne Contaminants. What do the terms low-, medium-, and Use the stoppers to prevent oxygen condensation and ice buildup. b`cC$NH?FC,p %.LYH 00= 200 0+ Contact with cryogenic liquids and their cold gases can produce effects on the skin similar to a thermal burn, as can contact with dry ice. Brief exposures that may not affect the hands can damage delicate tissues such as the eyes. 27 Min Read . Wyoming - 42 degrees Fahrenheit. All personnel using cyrogenic liquids must also be familiar with first aid procedures for treating frostbite: Return to Section 7 Guidelines & Safe Operating Procedures, Learn how to get free prescription safety glasses, 121 Gilman HallUniversity of CaliforniaBerkeley, CA 94720-1460(510) 664-5264, Graduate Office419 Latimer HallUniversity of CaliforniaBerkeley, CA 94720-1460(510) 642-5882, Graduate Office201 Gilman HallUniversity of CaliforniaBerkeley, CA 94720-1462(510) 642-2291, Admin, Finance, Technology Building Access College Relations Contact Us Diversity, Equity, & Inclusion Facilities Operations & Research Safety Information for Staff Information Technology Jobs Shipping & Receiving Staff Directory Website Update Request, Berkeley Website Berkeley News Campus Administration Campus Events Campus Map The Campaign for Berkeley Visiting Berkeley, Copyright 2023 UC Regents; all rights reserved, Advancing society through education and research, Guiding Outstanding Learners to Discover (GOLD), H&S Section 7: Safe Handling of Cryogenic Liquids. Cryogenic fluids with their boiling point in kelvins[13] and degree Celsius. When cryogenic liquids are spilled on the skin, a thin gaseous layer apparently forms next the skin. Close-toed shoes (without mesh tops) are required when handling cryogens. Even a brief contact with a cryogenic liquid is capable of causing tissue damage similar to that of thermal burns. f@TzgJ%@9m0^q&XWkk)E+vjZmj/tI{Yzb/[ ^4(=ZsG[J Dry ice is a super-cooled solid (carbon dioxide) that sublimes directly into gaseous carbon dioxide at 109.3 F. Sublimationis the transition of a substance directly from the solid to the gas state, without passing through the liquid state. Low pressure cylinders are equipped with a liquid valve for extracting liquid and a vent valve. Cryogenic liquid storage at warm temperature for an extended time can cause flash vaporization and produce extremely high pressure. rapid combustion or explosions) may occur if the system or process is not compatible with liquid oxygen (see below). horizon eye care mallard creek; cold temperatures associated with the use of cryogens. Examples of liquefied gases include: ammonia, chlorine, methane, natural gas and liquefied petroleum gas or liquid petroleum gas (lpg) which are propane and butane. cold temperatures associated with the use of cryogens Do NOT rub the frozen skin. 4 0 obj Refer to theGas and Cryogen Focus Sheetfor key design concepts. hb```f``rf`? You must still wear safety glasses underneath the face shield. [citation needed] This evolved in the late 1990s into the treatment of other parts. THE PRODUCTS YOU NEED, International Dictionary of Refrigeration, K.D. The use of an insulated pot holder is the preferred method of handling cold surfaces. Type a word, a phrase, or ask a question. Place cryotubes in a thick-wall container, e.g., a desiccator, or behind a safety shield while thawing. Lawrence Berkeley National Laboratory: ES&H Manual, Chapter 29: Safe Handling of cryogenic liquids http://www.lbl.gov/ehs/pub3000/CH29/CH29.html (accessed Dec 2013). - Risk Assessment and written procedures play an important role in the use of non-ionizing radiation Long cuffless trousers which cover the neck of the shoes should also be worn. [soeL&\Zi{hit^@4th_D jZ/I9&#OEc"V,dww8M-9e&g2^Cttj)$+0N,-\]Qp/. eF ^^K&e(LM There are two kinds of pressure regulator designs, which appear similar: single-stage and two-stage. Avoid contact of moisture with storage containers to prevent ice plugging of relief devices. When it falls below 18 percent, we do not have enough oxygen to function normally. Pamphlet P-12: Safe Handling of Cryogenic Liquids, Compressed Gas Association, March 2017, Cryogen Safety, National Institute of Standards and Technology (NIST), NFPA 55: Compressed Gases and Cryogenic Fluids, National Fire Protection Association, 2020 Edition, Laboratory Safety Guideline: Dry Ice, Harvard Campus Services Environmental Health and Safety, November 2019. Within 24 hours, 5-10 pounds of dry ice can sublimate. cold temperatures associated with the use of cryogens. When there is not enough air, asphyxiation and death can occur. Cold traps are used in instrumentation and other systems to prevent the introduction of liquids, vapors, or contaminants into the system. Closed toe shoes that cover the entire foot. Cryogenic temperatures may alter the physical characteristics of many materials. NMR: a. cold temperatures associated with the use of cryogens. These liquids may be stored in Dewar flasks, which are double-walled containers with a high vacuum between the walls to reduce heat transfer into the liquid. Concentrations of more than 0.5% (5000 ppm) carbon dioxide in the air can lead to unconsciousness. Cryogens are liquefied gases such as nitrogen, argon, or helium that pose significant hazards due to their low temperatures. Some dewar flasks have an outer vessel of liquid nitrogen for insulation. All cryogenic liquids are gases at normal temperatures and pressures. Unprotected skin can stick to materials that are cooled by cryogenic liquids and dry ice, similar to the way some children stick their tongues to flagpoles in the winter. There is A Scientific Reason That Cold Weather Could Cause Colds This is a serious hazard especially in enclosed or confined spaces. They can operate at up to 350 psig. When placed under pressure in specially designed storage containers (dewars), the gases condense to a liquid state and maintain very cold temperatures. When filling cryogenic liquids into equipment from an open dewar, avoid pouring over your head level, as a spill could cause serious injury. cold temperatures associated with the use of cryogens which of the following statements apply to a Chemical Risk Assessment? Cryogenic processing is not a substitute for heat treatment, but rather an extension of the heatingquenchingtempering cycle. Without adequate oxygen, one can lose consciousness in a few seconds and die of asphyxiation in a few minutes. These cold, heavy gases do not disperse well, tend to accumulate near the floor and displace air. This definition does not include liquid propane, liquid butane, liquid acetylene, or liquefied natural gas (methane). Supply oxygen if the victim has difficulty breathing and summon emergency medical help. Do not attempt to identify the compressed gas in the cylinder on your own. Always use the proper regulator for the gas in the cylinder. Single-stage regulators are used when precise control of delivery pressure is not required. Using cryogensin high ionizing radiation fields can generate ozone or nitrogen oxides. Dewar flasks are non-pressurized, vacuum-jacketed vessels, somewhat like a thermos bottle, designed for cryogenic liquids. K,k=1.7102s1. Long sleeve shirts are also recommended for arm protection. Cylinder manufacturers include engraved markings on cylinders to allow proper identification of substances in the container. Chapter 47. Cryogenics - Ashrae Since all cryogenic liquids and their cold boil-off vapors are extremely cold they can rapidly freeze human tissue and cause frostbite. As all alloys do not have the same chemical constituents, the tempering procedure varies according to the material's chemical composition, thermal history and/or a tool's particular service application. The concentration of oxygen in the condensed air will increase and lead to oxygen enriched conditions. The danger is that liquid nitrogen vaporizes so quickly that it displaces oxygen. Cryogenic temperatures are most easily achieved and maintained with the aid of liquefied gases, or cryogens, the most commonly used being nitrogen and helium. Connection fittings, stamped Compressed Gas Association (CGA) numbers, plaquesand/or decals on the regulator indicate for which gas the regulator is designed. One volume of a cryogenic liquid will expand to about 700 equivalents of gas when evaporated. cold temperatures associated with the use of cryogens. Do not rub the affected area as rubbing can cause further damage. Cryogenic fluids have large liquid-to-gas expansion ratios: These ratios mean that any accidental release or overflow of these cryogenic liquids will quickly boil into gas and createan asphyxiation hazardby displacing the oxygen content of the surrounding area. The extremely low temperatures associated with cryogenic liquids can easily condense moisture from the air and cause ice formation. 276 0 obj <>stream lab safety fundamentals Flashcards | Quizlet The College of Chemistry is consistently ranked as one of the best places on earth to learn, teach, and create new tools in the chemical sciences. The verdict: Cold weather does not cause colds. Oxygen deficiency monitors should be used in these areas. The term "high temperature cryogenic" describes temperatures ranging from above the boiling point of liquid nitrogen, 195.79C (77.36K; 320.42F), up to 50C (223K; 58F). Ensure that all equipment and containers are free of oil, grease, dirt or other materials which may create a hazardous condition upon contact with the cryogenic liquid. The information contained in this article is intended for general information purposes only and is based on information available as of the initial date of publication. This type of cylinder has valves for filling and dispensing the cryogenic liquid and a pressure-control valve with a bursting disk as backup protection. The SOP should include the manufacturers instructions regarding the use of and controls for commercially obtained cryogen equipment. This ice can cause components or systems to malfunction (e.g., can plug vent lines and impede valve operation) or can damage piping systems. Include procedural information regarding the use of equipment. All cylinders should bear a cylinder status tag stating one of the three conditions: full, in-serviceor empty. The term cryogenic means producing or related to low temperatures. 22 febrero, 2022 . Pressure regulators lower the gas pressure to a useable level. Physical Effects of Cryogenic Liquids and Dry Ice. Since all cryogenic liquids and their cold boil-off vapors are extremely cold they can rapidly freeze human tissue and cause frostbite. At 660. Apply CPR if the victim's breathing has stopped. Division of Research Safety Piping and tubing containing gases must be carefully designed. Be sure to contact the manufacturer if you are unsure of a cylinder's contents. Liquid helium, liquid hydrogen and liquid oxygen present additional hazards that liquid nitrogen and liquid argon do not. No representation is made that the information or references are complete or remain current. assume you are working with an acutely toxic chemical; select all administrative controls relevant for your project. Each cryogenic liquid or dry ice can cause specific health effects. Consult each materials SDS for specific guidance. Cryogens | Environmental Health & Safety (EHS) | The University of Appropriate PPE is still required when transporting cryogenic liquids around buildings. K,k=7.2104s1;660.\ \mathrm { K },\ k = 7.2 \times 10 ^ { - 4 }\ \mathrm { s } ^ { - 1 };660. NEVER pour cryogenic liquids down the drain, as the pipes are not made to withstand the low temperature. Wear cryogenic gloves and eye protection when transporting containers. low temperatures [below -153C (-243F)] . Be sure to contact the manufacturer if you are unsure of cylinder contents. The dewar should be kept as low to the ground as possible when using a dolly or cart for transportation. They are colorless, odorless and extremely cold. Even a brief contact with a cryogenic liquid is capable of causing tissue damage similar to that of thermal burns. <>/ExtGState<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/Annots[ 57 0 R 58 0 R] /MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Copyright 2023 The Board of Trustees of the University of Illinois. Store all cryogenic liquids away from combustible material and do not leave containers uncovered for long periods of times. A cryogen or cryogenic liquid is defined by the National Institute for Standards and Technology (NIST) as any liquid with a boiling point below 93K (-180C or -240F) at 1 atmosphere of pressure. When filling tanks or dewars with cryogens you'll want to cover your legs, feet, arms, hands and face to protect against splashes. endstream endobj startxref Shut off the source of vacuum if it is present. Cryotubes stored under liquid nitrogen can explode while thawing. Typical laboratory Dewar flasks are spherical, made of glass and protected in a metal outer container. Dewar flasks for extremely cold liquids such as liquid helium have another double-walled container filled with liquid nitrogen. x][~7M67 0NI;8HFFPL_u~VU7/5#`dI]U_TM]74jK7W?_}UOM! Oxygen is not flammable, but it vigorously accelerates and supports combustion. stream There are various cryogenic detectors which are used to detect particles. "When the . Compressed gas is a generic term used for describing compressed gases, liquefied compressed gases, refrigerated liquefied gases (cryogenic gases) and dissolved gases. Therefore, always consult with the most appropriate reference when selecting materials for cryogenic applications. Use an appropriate transfer line with phase separator to avoid splashing when filling into an open container. Personal Protective Equipment for Cryogenic Liquids and Dry Ice Safety. Cryogen gloves are usually loose fitting and easy to remove quickly. Liquid cryogens have an extremely low temperature. Never used heat resistant gloves to handle cryogen. Use care in transporting fragile cryogenic containers. Do not remove manufacturer applied labels. The sudden boiling of the cryogenic liquid is a significant hazard. Violent reactions (e.g. Solid carbon dioxide, referred to as dry ice, also has handling hazards due to its extreme cold temperature (-78 C). In the case of a large spill or rupture of a container, evacuate the area while alerting others.